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ALIMENTARY TRACT AND METABOLISM › DRUGS FOR ACID RELATED DISORDERS › ANTACIDS › Aluminium compounds
aloglutamol
A02AB06
Forms & Strengths
- Oral suspension
- Chewable tablets
Adult Dosing
- 1-2 tablets or 5-10 mL suspension as needed for dyspepsia or hyperacidity
- Administered after meals and at bedtime
Pediatric Dosing
- Safety and efficacy not well established in pediatric patients
- Use generally avoided or restricted per specific product labeling and clinician guidance
Indications
- Symptomatic relief of hyperacidity associated with peptic ulcer disease
- Gastritis
- Gastroesophageal reflux disease (GERD)
- Heartburn
Mechanism of Action
- Acts as an antacid by neutralizing gastric hydrochloric acid
- Increases gastric pH
- Provides mucosal protection through buffering action
Contraindications
- Hypersensitivity to aluminum or magnesium compounds
- Severe renal impairment
- Hypophosphatemia
Adverse Reactions
- Constipation
- Diarrhea
- Hypophosphatemia with prolonged use
- Aluminum accumulation in renal impairment
Drug Interactions
- May decrease absorption of concurrently administered oral medications including tetracyclines, iron, and fluoroquinolones
- Binding can be mitigated by separating administration times by 2-3 hours
Curated Content: Needs Vetting Before Put to Clinical Use