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ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › Other drugs for functional gastrointestinal disorders
idanpramine
A03AX06
Forms & Strengths
- Oral tablets: 10 mg
- Oral tablets: 25 mg
Adult Dosing
- Functional gastrointestinal disorders: 10 mg to 25 mg orally three times daily
- Maximum daily dose: 75 mg
Pediatric Dosing
- Safety and efficacy in pediatric patients not established
- Use generally not recommended in children under 12 years of age
Indications
- Symptomatic relief of functional gastrointestinal disorders
- Management of visceral pain associated with smooth muscle spasms
Mechanism of Action
- Acts as an antispasmodic agent on gastrointestinal smooth muscle
- Exerts anticholinergic and direct myotropic effects to reduce gut motility and spasm
Contraindications
- Hypersensitivity to idanpramine or related compounds
- Glaucoma (narrow-angle)
- Gastrointestinal obstruction, ileus, or toxic megacolon
- Severe urinary retention related to prostatic hyperplasia
Adverse Reactions
- Dry mouth
- Blurred vision
- Constipation
- Drowsiness
- Urinary retention
- Tachycardia
Drug Interactions
- Enhancement of anticholinergic effects when co-administered with tricyclic antidepressants or antihistamines
- Potential antagonism of gastrointestinal prokinetic agents (e.g., metoclopramide, cisapride)
Curated Content: Needs Vetting Before Put to Clinical Use