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ALIMENTARY TRACT AND METABOLISM › DRUGS FOR CONSTIPATION › DRUGS FOR CONSTIPATION › Bulk-forming laxatives
methylcellulose
A06AC06
Forms & Strengths
- Oral powder: 1.5g, 2g packets
- Oral tablets: 500mg
- Suspension: 1g/10mL
Adult Dosing
- Constipation: 1-2 tablespoons (15-30mL) daily
- Irritable bowel syndrome: 1-2 tablespoons (15-30mL) daily
- Diverticulitis: 1 tablespoon (15mL) daily
Pediatric Dosing
- Children 6-12 years: 1/2 to 1 teaspoonful daily
- Children under 6 years: not recommended
Indications
- Treatment of constipation
- Treatment of diverticulitis
- Treatment of irritable bowel syndrome
- Bowel preparation for radiologic examination
Mechanism of Action
- Increases bulk of stool by absorbing water and swelling
- Stimulates intestinal motility and promotes regular bowel movements
Contraindications
- Hypersensitivity to methylcellulose
- Intestinal obstruction
- Gastrointestinal ulcers or hemorrhage
Adverse Reactions
- Gastrointestinal: bloating, gas, abdominal cramps
- Allergic reactions: rash, itching, urticaria
Drug Interactions
- Reduced absorption of tetracyclines, warfarin
- Interference with absorption of other oral medications
Curated Content: Needs Vetting Before Put to Clinical Use