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ALIMENTARY TRACT AND METABOLISM › ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS › ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS › Centrally acting antiobesity products
lorcaserin
A08AA11
Adult Dosing
- 10mg twice daily
- Maximum daily dose: 20mg
Pediatric Dosing
- Safety and efficacy not established in patients younger than 18 years
Indications
- Chronic weight management in adults with BMI of 30 or higher
- Chronic weight management in adults with BMI of 27 or higher with at least one weight-related condition
Mechanism of Action
- Selective 5-HT2C receptor agonist
- Increases satiety and reduces hunger
Contraindications
- Pregnancy
- Hypersensitivity to lorcaserin
Adverse Reactions
- Headache
- Dizziness
- Fatigue
- Nausea
- Dry mouth
- Constipation
Drug Interactions
- Concomitant use with other serotonergic agents may increase risk of serotonin syndrome
- Concomitant use with CYP2D6 substrates may increase risk of adverse reactions
Curated Content: Needs Vetting Before Put to Clinical Use