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BLOOD AND BLOOD FORMING ORGANS › ANTIANEMIC PREPARATIONS › IRON PREPARATIONS › Iron bivalent, oral preparations
ferrous gluconate
B03AA03
Forms & Strengths
- Tablets: 300 mg (contains approximately 35 mg elemental iron)
- Tablets: 324 mg (contains approximately 37.5 mg elemental iron)
- Capsules: 86 mg (contains approximately 10 mg elemental iron)
- Elixir: 300 mg/5 mL (contains approximately 35 mg elemental iron per 5 mL)
Adult Dosing
- Iron deficiency anemia: 300 mg to 324 mg orally 1 to 2 times daily
- Prophylaxis of iron deficiency: 300 mg orally daily
Pediatric Dosing
- Children > 12 years: 300 mg orally 1 to 2 times daily for iron deficiency anemia
- Infants and children < 12 years: 3 mg/kg/day to 6 mg/kg/day of elemental iron divided into 3 daily doses
Indications
- Treatment of iron deficiency anemia
- Prevention and treatment of iron deficiency states
Mechanism of Action
- Replaces iron found in hemoglobin, myoglobin, and other enzymes
- Allows the transportation of oxygen via hemoglobin through the blood to tissues
Contraindications
- Hemochromatosis
- Hemosiderosis
- Hemolytic anemia
- Hypersensitivity to iron salts
Adverse Reactions
- Constipation
- Dark stools
- Nausea
- Epigastric pain
- Diarrhea
- Vomiting
Drug Interactions
- Antacids and proton pump inhibitors decrease iron absorption
- Ascorbic acid increases iron absorption
- Fluoroquinolones, tetracyclines, and levodopa absorption is decreased by concurrent iron administration
- Dimercaprol forms toxic complexes with iron
Curated Content: Needs Vetting Before Put to Clinical Use