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BLOOD AND BLOOD FORMING ORGANS › ANTIANEMIC PREPARATIONS › IRON PREPARATIONS › Iron bivalent, oral preparations
ferrous tartrate
B03AA08
Forms & Strengths
- Oral drops: varies by regional formulation
- Oral syrup: varies by regional formulation
- Oral tablets: varies by regional formulation
Adult Dosing
- Iron deficiency anemia: 100 to 200 mg elemental iron daily divided into 1 to 3 doses
- Prophylaxis: 50 to 100 mg elemental iron daily
Pediatric Dosing
- Infants and children: 3 to 6 mg/kg/day of elemental iron in divided doses, adjusted based on age and severity of deficiency
Indications
- Treatment of iron deficiency anemia
- Prevention and treatment of iron deficiency states
Mechanism of Action
- Replaces iron found in hemoglobin, myoglobin, and other enzymes
- Enables the transport of oxygen via hemoglobin through the binding of ferrous iron to porphyrin and globulin proteins
Contraindications
- Hypersensitivity to ferrous salts or any component of the formulation
- Hemochromatosis and hemosiderosis
- Hemolytic anemia
- Aplastic or pernicious anemia unless accompanied by iron deficiency
Adverse Reactions
- Constipation
- Diarrhea
- Nausea and vomiting
- Epigastric pain
- Dark or black stools
Drug Interactions
- Antacids and proton pump inhibitors decrease iron absorption
- Oral tetracyclines and fluoroquinolones: decreased absorption of both the antibiotic and iron due to chelation
- Ascorbic acid (Vitamin C) increases iron absorption
Curated Content: Needs Vetting Before Put to Clinical Use