← Search & browse all drugs
BLOOD AND BLOOD FORMING ORGANS › ANTIANEMIC PREPARATIONS › IRON PREPARATIONS › Iron bivalent, oral preparations
ferrous sodium citrate
B03AA12
Forms & Strengths
- Oral tablets containing ferrous sodium citrate
- Liquid oral preparations (varies by region)
Adult Dosing
- Iron deficiency anemia: 50 mg to 200 mg elemental iron daily in divided doses, adjusted based on response and tolerability
Pediatric Dosing
- Iron deficiency anemia (pediatric): 3 mg to 6 mg/kg/day of elemental iron in divided doses, determined by weight and severity
Indications
- Treatment and prevention of iron deficiency anemia
- Prophylaxis of iron deficiency during periods of increased demand (e.g., pregnancy, rapid growth)
Mechanism of Action
- Provides elemental iron which is incorporated into hemoglobin, myoglobin, and various enzymes
- Replenishes body iron stores in the reticuloendothelial system
Contraindications
- Hypersensitivity to iron salts or any component of the formulation
- Hemochromatosis and hemosiderosis
- Hemolytic anemia, thalassemia, and other non-iron deficiency anemias unless concurrent iron deficiency is confirmed
Adverse Reactions
- Gastrointestinal irritation, nausea, vomiting, epigastric pain
- Constipation, diarrhea
- Dark or black stools (benign)
Drug Interactions
- Decreased iron absorption when co-administered with antacids, calcium supplements, proton pump inhibitors, and H2-receptor antagonists
- Reduced absorption of oral tetracyclines, fluoroquinolones, levodopa, and levothyroxine due to chelation; separate administration times
Curated Content: Needs Vetting Before Put to Clinical Use