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BLOOD AND BLOOD FORMING ORGANS › ANTIANEMIC PREPARATIONS › IRON PREPARATIONS › Iron trivalent, oral preparations
ferric sodium citrate
B03AB01
Forms & Strengths
- Ferric sodium citrate 50mg iron/ml solution for injection
- Ferric sodium citrate 100mg iron/ml solution for injection
Adult Dosing
- Total dose of 1000mg iron for 70kg patient, divided into smaller doses
- Maximum single dose 200-400mg iron, repeated every 4 days
- Treatment duration 8-10 doses
Pediatric Dosing
- Dose calculated based on individual iron need
- 50-100mg iron/kg body weight total dose for iron deficiency anemia
- Not recommended for children under 4 months
Indications
- Treatment of iron deficiency anemia
- Prevention of iron deficiency anemia in chronic kidney disease patients on dialysis
Mechanism of Action
- Replenishes iron stores in the body
- Essential for the production of hemoglobin
- Stimulates erythropoiesis
Contraindications
- Known hypersensitivity to ferric sodium citrate
- Acute hepatitis
Adverse Reactions
- Hypersensitivity reactions, such as anaphylaxis
- Flush, rash, pruritus, urticaria
- Nausea, vomiting, diarrhea, abdominal pain
- Hypotension, chest pain, headache
Drug Interactions
- Reduced absorption with concomitant oral iron therapy
- Incompatibility with bicarbonate-containing solutions
- Interaction with antihypertensive medications, exacerbating hypotensive effect
Curated Content: Needs Vetting Before Put to Clinical Use