← Search & browse all drugs
CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES › Other cardiac stimulants
xamoterol
C01CX07
Adult Dosing
- 200 mg orally twice daily
Pediatric Dosing
- Safety and efficacy not established in children
Indications
- Mild to moderate heart failure
Mechanism of Action
- Partial beta-1 adrenoceptor agonist
- Exerts positive inotropic effect while acting as a competitive antagonist against high catecholamine levels
Contraindications
- Severe heart failure (NYHA Class IV)
- Hypersensitivity to xamoterol
- Resting tachycardia
- Severe uncorrected heart block
Adverse Reactions
- Palpitations
- Dizziness
- Headache
- Nausea
- Rash
Drug Interactions
- Beta-blockers may antagonize the positive inotropic effects of xamoterol
- Concurrent use with other sympathomimetics may increase cardiovascular side effects
Curated Content: Needs Vetting Before Put to Clinical Use