← Search & browse all drugs
CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE › Local anesthetics
pramocaine
C05AD07
Forms & Strengths
- Topical cream: 1%
- Topical ointment: 1%
- Topical lotion: 1%
- Topical gel: 1%
Adult Dosing
- Apply to affected area up to 3 to 4 times daily
- For anorectal use: apply topically to the affected area up to 4-5 times daily, or after each bowel movement
Pediatric Dosing
- Children under 2 years: consult a physician
- Children 2 years and older: apply topically up to 3 to 4 times daily
Indications
- Temporary relief of pain and itching associated with minor skin irritations
- Temporary relief of anorectal itching and discomfort associated with hemorrhoids
Mechanism of Action
- Acts as a topical surface anesthetic
- Stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthesia
Contraindications
- Hypersensitivity to pramocaine or any component of the formulation
- Application to blistered or broken skin in large amounts
- Ophthalmic use
Adverse Reactions
- Local burning
- Stinging
- Erythema
- Contact dermatitis
Drug Interactions
- No significant systemic drug interactions identified due to minimal systemic absorption with topical administration
- Additive local anesthetic effects possible if co-administered with other topical anesthetics on the same skin area
Curated Content: Needs Vetting Before Put to Clinical Use