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CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE › Other agents for treatment of hemorrhoids and anal fissures for topical use
zinc preparations
C05AX04
Forms & Strengths
- Ointment, Zinc Oxide 10% - 40%
- Cream, Zinc Oxide 15% - 20%
- Paste, Zinc Oxide 25%
- Suppositories, Zinc Oxide 11 mg - 295 mg
Adult Dosing
- Topical (Diaper dermatitis, chafed skin): Apply a thin layer to affected area as needed.
- Rectal (Hemorrhoids): Insert 1 suppository rectally up to 4 times daily or after each bowel movement.
Pediatric Dosing
- Topical (Diaper dermatitis, infants and children): Apply liberally to affected area with each diaper change as needed.
Indications
- Skin protection and treatment of minor skin irritations (e.g., diaper rash, cuts, burns)
- Temporary relief of anorectal discomfort, itching, and burning associated with hemorrhoids
Mechanism of Action
- Zinc oxide acts as a mild astringent, protective, and soothing agent on the skin and mucous membranes.
- Forms a physical barrier on the skin to prevent irritants and moisture from contacting compromised tissue.
Contraindications
- Hypersensitivity to zinc or any component of the formulation
- Application to serious, deep, or puncture wounds, or severe burns without medical supervision
Adverse Reactions
- Local skin irritation, stinging, or redness at application site
- Allergic contact dermatitis (rare)
Drug Interactions
- No significant systemic drug-interactions expected with topical or rectal anorectal zinc preparations.
- Avoid concurrent application of other topical medications on the same skin area unless directed by a physician.
Curated Content: Needs Vetting Before Put to Clinical Use