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glucose, combinations

C05BB56

Forms & Strengths

Suppository: Variable combinations containing glucose and astringents/protectants
Ointment/Cream: Topical formulations for anorectal use containing glucose and protectants

Adult Dosing

Suppositories: Insert 1 suppository rectally up to 3-4 times daily, especially after bowel movements
Ointment: Apply a thin layer to the affected anorectal area up to 3-4 times daily

Pediatric Dosing

Safety and efficacy in pediatric patients have not been established; use generally not recommended unless directed by a physician

Indications

Temporary relief of pain, burning, and itching associated with hemorrhoids and other anorectal disorders
Reduction of swelling and protection of irritated anorectal tissue

Mechanism of Action

Glucose acts locally to exert a hypertonic osmotic effect, helping to reduce local edema and tissue swelling in hemorrhoids
Combined protectants form a physical barrier over inflamed rectal mucosa to prevent irritation from fecal matter

Contraindications

Hypersensitivity to glucose or any component of the formulation
Presence of anorectal bleeding, unless diagnosed by a physician

Adverse Reactions

Local burning, stinging, or irritation upon application
Allergic contact dermatitis or hypersensitivity reactions

Drug Interactions

No significant systemic drug interactions identified due to minimal systemic absorption from topical anorectal administration
Concurrent use of other topical anorectal products in the same area should be avoided to prevent additive irritation

Curated Content: Needs Vetting Before Put to Clinical Use