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CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › CAPILLARY STABILIZING AGENTS › Other capillary stabilizing agents
tribenoside
C05CX01
Forms & Strengths
- Cream: 5%
- Suppositories: 400 mg
Adult Dosing
- Hemorrhoids (internal/external): Apply cream 2 times daily (morning and evening)
- Suppositories: 1 suppository rectally 1-2 times daily until symptoms subside
Pediatric Dosing
- Safety and efficacy not established in pediatric patients; use not generally recommended
Indications
- Internal and external hemorrhoids
- Perianal venous congestion and inflammation
Mechanism of Action
- Acts locally as a vascular protective agent
- Reduces capillary permeability and improves vascular tone
- Exerts anti-inflammatory and analgesic effects on local tissues
Contraindications
- Hypersensitivity to tribenoside, lidocaine (if combination product), or any excipients
- Severe hepatic impairment
Adverse Reactions
- Local burning sensation or irritation at application site
- Allergic skin reactions (contact dermatitis, rash)
- Increased bowel motility (rarely with suppositories)
Drug Interactions
- No clinically significant systemic drug interactions reported due to minimal systemic absorption
- Avoid concurrent application of other local rectal preparations in the same area
Curated Content: Needs Vetting Before Put to Clinical Use