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CARDIOVASCULAR SYSTEM › BETA BLOCKING AGENTS › BETA BLOCKING AGENTS AND OTHER DIURETICS › Beta blocking agents, non-selective, and other diuretics
bopindolol and other diuretics
C07CA17
Forms & Strengths
- Tablets: 1mg, 2mg, 4mg, 8mg
- Combination with diuretics: 1mg + 6.25mg hydrochlorothiazide
Adult Dosing
- Initial dose: 1-2mg once daily
- Maintenance dose: 2-8mg once daily
- Maximum dose: 8mg once daily
Pediatric Dosing
- Not established for pediatric use
- Use with caution in patients over 12 years old
Indications
- Treatment of hypertension
- Treatment of angina pectoris
- Prophylaxis of migraine attacks
Mechanism of Action
- Beta-1 selective adrenergic receptor blocker
- Decreases cardiac output and heart rate
- Reduces peripheral vascular resistance
Contraindications
- Hypersensitivity to bopindolol
- Cardiogenic shock
- Severe bronchial asthma
- Second- or third-degree heart block
Adverse Reactions
- Fatigue
- Dizziness
- Headache
- Nausea and vomiting
- Bronchospasm
Drug Interactions
- Verapamil: increased risk of heart block
- Clonidine: increased risk of rebound hypertension
- Insulin and oral hypoglycemics: masking of hypoglycemic symptoms
Curated Content: Needs Vetting Before Put to Clinical Use