← Search & browse all drugs
CARDIOVASCULAR SYSTEM › AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM › ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN › Angiotensin II receptor blockers (ARBs), plain
tasosartan
C09CA05
Forms & Strengths
- Tablets: 10mg, 20mg, 40mg
- Oral solution: 5mg/5mL
Adult Dosing
- Hypertension: 10-40mg once daily
- Heart failure: 20-40mg once daily
Pediatric Dosing
- Safety and efficacy not established in pediatric patients
- Not recommended for use in children under 18 years
Indications
- Hypertension
- Heart failure
Mechanism of Action
- Selective angiotensin II receptor antagonist
- Inhibits vasoconstrictive and aldosterone-secreting effects of angiotensin II
Contraindications
- Hypersensitivity to tasosartan or other angiotensin II receptor antagonists
- Pregnancy, especially second and third trimesters
Adverse Reactions
- Hypotension
- Dizziness
- Headache
- Hyperkalemia
- Increased serum creatinine
Drug Interactions
- NSAIDs: increased risk of hyperkalemia and acute kidney injury
- Potassium-sparing diuretics: increased risk of hyperkalemia
- Warfarin: monitor INR
Curated Content: Needs Vetting Before Put to Clinical Use