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DERMATOLOGICALS › ANTIFUNGALS FOR DERMATOLOGICAL USE › ANTIFUNGALS FOR TOPICAL USE › Imidazole and triazole derivatives
eberconazole
D01AC17
Adult Dosing
- Apply to affected area once or twice daily for 2 to 4 weeks
- Rub gently into clean, dry skin
Pediatric Dosing
- Safety and efficacy not established in children under 12 years
- Use in adolescents same as adult dosing if clinically indicated
Indications
- Topical treatment of superficial dermatomycoses
- Tinea corporis, tinea cruris, and tinea pedis
- Cutaneous candidiasis and pityriasis versicolor
Mechanism of Action
- Broad-spectrum topical imidazole antifungal
- Inhibits fungal lanosterol 14-alpha-demethylase
- Blocks ergosterol biosynthesis, leading to increased fungal cell membrane permeability and lysis
Contraindications
- Hypersensitivity to eberconazole or other imidazole antifungals
- Ophthalmic use
Adverse Reactions
- Local skin irritation
- Erythema
- Pruritus
- Burning sensation at application site
Drug Interactions
- No significant systemic drug interactions expected due to minimal percutaneous absorption
- Avoid concurrent use of other topical agents on the same skin area unless directed
Curated Content: Needs Vetting Before Put to Clinical Use