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DERMATOLOGICALS › PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS › CICATRIZANTS › Other cicatrizants
sodium chlorite
D03AX11
Forms & Strengths
- Topical gel/solution various concentrations (often activated with acid)
- Oral solution/drops marketed illegally as 'Miracle Mineral Solution' (MMS) - unapproved
Adult Dosing
- Topical: Apply thin layer to affected skin areas as directed by specific product protocol
- Oral (MMS): No approved medical indication; ingestion is dangerous and strongly contraindicated
Pediatric Dosing
- Topical: Safety and efficacy not established in children
- Oral: Contraindicated and highly toxic in pediatric populations
Indications
- Topical antiseptic and wound/ulcer debridement agent in specific veterinary or niche human formulations
- Note: Widely promoted via unverified sources as a cure-all, but lacks FDA approval for systemic use
Mechanism of Action
- Acts as an oxidizing agent releasing chlorine dioxide
- Exerts antimicrobial and debriding effects via protein denaturation and destruction of microbial cell walls
Contraindications
- Systemic or oral ingestion (causes severe toxicity)
- Known hypersensitivity to chlorite or chlorine dioxide compounds
- Application to large, deep, or highly vascularized open wounds
Adverse Reactions
- Topical: Local skin irritation, burning, erythema, and chemical burns
- Oral ingestion: Nausea, vomiting, severe diarrhea, methemoglobinemia, hemolysis, acute renal failure, and potentially death
Drug Interactions
- Topical: Avoid concurrent application of other topical irritants or keratolytics
- Systemic/Oral: Interacts with numerous substances due to extreme oxidative potential; concurrent antioxidant ingestion may blunt acute toxicity but does not prevent systemic harm
Curated Content: Needs Vetting Before Put to Clinical Use