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DERMATOLOGICALS › ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE › CHEMOTHERAPEUTICS FOR TOPICAL USE › Antivirals
ibacitabine
D06BB08
Adult Dosing
- Apply topically 3-5 times daily
- Use for 8-12 days
Pediatric Dosing
- Apply topically 3-5 times daily for children over 2 years old
- Use under medical supervision for children under 2 years old
Indications
- Herpes simplex infections
- Varicella zoster infections
- Herpes zoster infections
Mechanism of Action
- Inhibits viral DNA synthesis
- Interferes with viral replication
Contraindications
- Hypersensitivity to ibacitabine or its components
- Untreated glaucoma
- Epithelial keratitis
Adverse Reactions
- Local irritation
- Itching
- Burning
- Hypersensitivity reactions
Drug Interactions
- Increased toxicity when used with other antiviral agents
- Interference with ocular medications
- Combination with steroids may increase intraocular pressure
Curated Content: Needs Vetting Before Put to Clinical Use