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DERMATOLOGICALS › ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE › CHEMOTHERAPEUTICS FOR TOPICAL USE › Antivirals
sinecatechins
D06BB12
Adult Dosing
- Apply 0.5 cm strand of ointment to each external genital wart 3 times daily
- Continue treatment until complete clearance of warts, up to a maximum of 16 weeks
Pediatric Dosing
- Safety and efficacy not established in patients below 18 years of age
Indications
- Treatment of external genital warts (Condylomata acuminata) and perianal warts in immunocompetent patients
Mechanism of Action
- Botanical extract from green tea leaves with catechins as active ingredients
- Exact mechanism of action in treating genital warts is unknown
- Exhibits antioxidant, immunomodulatory, anti-proliferative, and antiviral effects in vitro
Contraindications
- Hypersensitivity to sinecatechins, green tea extract, or any ointment excipients
- Use in immunosuppressed patients
Adverse Reactions
- Local skin reactions (erythema, pruritus, burning, pain, ulceration, edema, induration)
- Phimosis
- Inguinal lymphadenitis
- Scarring
Drug Interactions
- Avoid concurrent use of other topical treatments on the same affected area
- No formal drug-interaction studies have been performed
Curated Content: Needs Vetting Before Put to Clinical Use