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DERMATOLOGICALS › CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS › CORTICOSTEROIDS, PLAIN › Corticosteroids, moderately potent (group II)
alclometasone
D07AB10
Forms & Strengths
- cream 0.05%
- ointment 0.05%
- lotion 0.05%
Adult Dosing
- apply thinly 2-3 times daily
- max 3 weeks for face and neck
- discontinue when control achieved
Pediatric Dosing
- apply thinly 2-3 times daily
- children over 1 year
- use for shortest duration
- avoid face and neck
Indications
- mild to moderate inflammatory skin conditions
- atopic dermatitis
- eczema
- contact dermatitis
- psoriasis
Mechanism of Action
- inhibits prostaglandin synthesis
- reduces inflammation and pruritus
- modulates immune response
- decreases edema and cell infiltration
Contraindications
- hypersensitivity to alclometasone
- untreated cutaneous infections
- rosacea
- perioral dermatitis
Adverse Reactions
- burning sensation
- pruritus
- irritation
- folliculitis
- hypertrichosis
- skin atrophy
Drug Interactions
- increased risk of cataracts with corticosteroids
- systemic absorption with CYP3A4 inhibitors
Curated Content: Needs Vetting Before Put to Clinical Use