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DERMATOLOGICALS › CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS › CORTICOSTEROIDS, PLAIN › Corticosteroids, potent (group III)
methylprednisolone aceponate
D07AC14
Forms & Strengths
- cream 0.1%
- ointment 0.1%
- lotion 0.1%
Adult Dosing
- apply a thin layer to affected skin areas once daily
- treatment duration depends on condition being treated
Pediatric Dosing
- apply a thin layer to affected skin areas once daily in children over 4 months
- use in children under 4 months is not recommended
Indications
- atopic dermatitis
- psoriasis
- contact dermatitis
- seborrheic dermatitis
Mechanism of Action
- methylprednisolone aceponate is a corticosteroid with anti-inflammatory and immunosuppressive properties
- acts by modifying the body's immune response to various diseases
Contraindications
- hypersensitivity to methylprednisolone aceponate
- skin infections (e.g., impetigo, herpes simplex, varicella, rosacea, acne)
- do not use on the face, except for short periods
Adverse Reactions
- burning sensation
- itching
- redness
- irritation
- folliculitis
- perioral dermatitis
- pigmentation changes
- skin atrophy
Drug Interactions
- concomitant use with other corticosteroids may increase the risk of adverse reactions
- corticosteroids can interact with other medications e.g. ritonavir, itraconazole, ketoconazole
Curated Content: Needs Vetting Before Put to Clinical Use