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DERMATOLOGICALS › CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS › CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS › Corticosteroids, moderately potent, combinations with antiseptics
hydrocortisone butyrate and antiseptics
D07BB04
Forms & Strengths
- cream 1mg/g
- ointment 1mg/g
Adult Dosing
- apply 1-2 times daily to affected area
- do not exceed 50g/week
Pediatric Dosing
- apply 1 time daily to affected area
- do not exceed 20g/week for children under 12
- consult physician for children under 3 months
Indications
- mild to moderate atopic dermatitis
- contact dermatitis
- eczematous dermatitis
Mechanism of Action
- hydrocortisone butyrate is a glucocorticoid with anti-inflammatory and immunosuppressive properties
- hydrocortisone butyrate inhibits phospholipase A2, reducing inflammation
Contraindications
- hypersensitivity to hydrocortisone butyrate or antiseptics
- untreated bacterial, fungal or viral skin infections
- rosacea, acne, or perioral dermatitis
Adverse Reactions
- burning sensation
- itching
- dryness
- folliculitis
- perioral dermatitis
- allergic contact dermatitis
Drug Interactions
- avoid concurrent use with other corticosteroids
- caution with concomitant use of antifungals
- increased skin irritation with astringents or abrasives
Curated Content: Needs Vetting Before Put to Clinical Use