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DERMATOLOGICALS › CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS › CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS › Corticosteroids, moderately potent, combinations with antibiotics
fluorometholone and antibiotics
D07CB03
Forms & Strengths
- 0.1% fluorometholone with 0.5% neomycin sulfate ophthalmic suspension
- 0.1% fluorometholone with 0.5% polymyxin B sulfate ophthalmic suspension
- 0.1% fluorometholone with 0.5% sulfacetamide sodium ophthalmic suspension
Adult Dosing
- 1-2 drops into the conjunctival sac 2-4 times daily
- Treatment duration: up to 2 weeks
- For severe infections, consult an ophthalmologist
Pediatric Dosing
- Same as adult dosing
- Use with caution in children under 2 years
- Monitor for signs of systemic absorption
Indications
- Bacterial conjunctivitis
- Blepharoconjunctivitis
- Keratoconjunctivitis
- Marginal corneal ulcers
Mechanism of Action
- Fluorometholone: anti-inflammatory corticosteroid
- Neomycin sulfate: aminoglycoside antibiotic
- Polymyxin B sulfate: polymyxin antibiotic
- Sulfacetamide sodium: sulfonamide antibiotic
Contraindications
- Hypersensitivity to fluorometholone or antibiotics
- Viral infections of the cornea
- Fungal infections of the eye
- Tuberculosis of the eye
Adverse Reactions
- Local irritation
- Burning sensation
- Blurred vision
- Increased intraocular pressure
- Systemic absorption in children
Drug Interactions
- Corticosteroids may interact with systemic antibiotics
- Concomitant use with other ophthalmic medications
- Potential for increased intraocular pressure with concomitant use of corticosteroids
- Monitor for signs of systemic absorption when used with other medications
Curated Content: Needs Vetting Before Put to Clinical Use