← Search & browse all drugs

desoximetasone

D07XC02

Forms & Strengths

Cream: 0.05%, 0.25%
Ointment: 0.05%, 0.25%
Gel: 0.05%
Spray: 0.25%

Adult Dosing

Apply a thin layer to affected areas 1-2 times daily
For plaque psoriasis: Apply 0.25% ointment or cream twice daily
For atopic dermatitis: Apply 0.05% cream or ointment twice daily

Pediatric Dosing

Apply a thin layer to affected areas 1-2 times daily for children over 12 years
Safety and efficacy not established in children under 12 years
Use 0.05% cream or ointment for children due to higher risk of adrenal suppression

Indications

Treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses
Plaque psoriasis
Atopic dermatitis
Contact dermatitis
Seborrheic dermatitis

Mechanism of Action

Desoximetasone is a potent topical corticosteroid with anti-inflammatory and immunosuppressive properties
Binds to specific receptors on skin cells, inhibiting the release of pro-inflammatory mediators
Reduces swelling, redness, and itching by inhibiting the immune response

Contraindications

Hypersensitivity to desoximetasone or any component of the formulation
Rosacea, perioral dermatitis, or dermatitis around the mouth
Acne vulgaris, acne rosacea, or perioral dermatitis
Occlusive dressing in children due to risk of adrenal suppression

Adverse Reactions

Skin atrophy, telangiectasia, and striae
Hypopigmentation, hypertrichosis, and allergic contact dermatitis
Burning, itching, stinging, and dryness at application site
Cushing's syndrome, adrenal suppression, and growth suppression in children

Drug Interactions

Corticosteroids may interact with other immunosuppressive agents, increasing the risk of infection
May enhance the effects of other topical corticosteroids
Concurrent use with other corticosteroids may increase the risk of adrenal suppression

Curated Content: Needs Vetting Before Put to Clinical Use