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DERMATOLOGICALS › CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS › CORTICOSTEROIDS, OTHER COMBINATIONS › Corticosteroids, potent, other combinations
mometasone
D07XC03
Forms & Strengths
- Ointment: 0.1%
- Cream: 0.1%
- Lotion: 0.1%
- Topical solution: 0.1%
- Inhalation powder: 100mcg, 200mcg
- Nasal spray: 50mcg
Adult Dosing
- Apply topical formulations to affected areas once daily
- Inhalation: 200-400mcg twice daily for asthma
- Nasal spray: 2 sprays (100mcg) in each nostril once daily for allergic rhinitis
Pediatric Dosing
- Topical: Apply to affected areas once daily, dosage depends on age and condition
- Inhalation (4 years and older): 100mcg twice daily for asthma
- Nasal spray (2 years and older): 1 spray (50mcg) in each nostril once daily for allergic rhinitis
Indications
- Treatment of inflammatory skin conditions (e.g. eczema, psoriasis)
- Prophylactic treatment of asthma
- Relief of symptoms of allergic rhinitis
- Treatment of nasal polyps
Mechanism of Action
- Corticosteroid with local anti-inflammatory effects
- Inhibits release of inflammatory mediators
- Suppresses immune response in target tissues
Contraindications
- Hypersensitivity to mometasone or other corticosteroids
- Untreated fungal, bacterial or viral skin infections
- Rosacea, acne, perioral dermatitis (topical formulations)
Adverse Reactions
- Local skin reactions (e.g. irritation, burning, itching)
- Thinning of skin, skin atrophy
- Nasal dryness, irritation, or bleeding (nasal spray)
- Cough, wheezing, or shortness of breath (inhalation powder)
Drug Interactions
- Ritonavir: may increase mometasone exposure
- Other CYP3A4 inhibitors: potential for increased mometasone levels
- Avoid concurrent use with other corticosteroids
Curated Content: Needs Vetting Before Put to Clinical Use