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DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Acridine derivatives
aminoacridine
D08AA02
Forms & Strengths
- Solution for topical use, 0.1% and 1.0%
- Cream, 0.1% and 0.5%
- Ointment, 0.1% and 0.5%
Adult Dosing
- Apply 1-2 times daily
- Use for 7-14 days
- For skin infections, apply thinly
Pediatric Dosing
- Avoid use in children under 2 years old
- For children over 2 years old, apply 1 time daily
- Not recommended for neonates
Indications
- Treatment of minor cuts and abrasions
- Treatment of minor burns
- Prevention of infection in minor injuries
Mechanism of Action
- Interferes with bacterial DNA, inhibiting growth
- Has a bacteriostatic effect at lower concentrations
- Exhibits antimicrobial properties against bacteria
Contraindications
- Hypersensitivity to aminoacridine
- Pregnancy and lactation
- Open wounds, deep puncture wounds
Adverse Reactions
- Skin irritation
- Allergic reactions
- Contact dermatitis
Drug Interactions
- Avoid concomitant use with other topical antimicrobials
- Interactions with systemic antibiotics not established
Curated Content: Needs Vetting Before Put to Clinical Use