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DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Quaternary ammonium compounds
benzalkonium
D08AJ01
Forms & Strengths
- Solution 0.13%
- Solution 0.5%
- Solution 1.0%
- Ointment 0.5%
- Gel 0.5%
- Concentrate for topical solution
Adult Dosing
- Apply 1-2 times daily to affected area
- Use as needed for wound cleansing
- Use as directed for skin disinfection
Pediatric Dosing
- Apply 1 time daily to affected area for children over 2 years
- Avoid use in children under 2 years unless instructed by physician
- Use as directed for skin disinfection in children over 2 years
Indications
- Skin disinfection
- Wound cleansing
- Preoperative skin preparation
- Antiseptic for minor cuts and scrapes
Mechanism of Action
- Disrupts cell membrane of microorganisms
- Inhibits bacterial enzyme activity
- Denatures proteins and nucleic acids of microorganisms
Contraindications
- Hypersensitivity to benzalkonium
- Deep or puncture wounds
- Serious burns
- Eye or ear infections
Adverse Reactions
- Local irritation
- Redness
- Itching
- Dryness
- Hypersensitivity reactions
Drug Interactions
- Incompatible with anionic surfactants
- Incompatible with soap
- May interact with other topical antiseptics
Curated Content: Needs Vetting Before Put to Clinical Use