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DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Quaternary ammonium compounds
cetrimonium
D08AJ02
Forms & Strengths
- Solution: 0.1-2%
- Cream: 0.2-2%
- Ointment: 0.2-5%
Adult Dosing
- Apply 0.2-2% solution or cream to affected area 2-3 times daily
- Apply 0.2-5% ointment to affected area 1-2 times daily
Pediatric Dosing
- Apply 0.1-1% solution or cream to affected area 2-3 times daily for children over 3 years
- Not recommended for children under 3 years
Indications
- Topical treatment of minor cuts and scrapes
- Treatment of minor burns
- Treatment of skin infections
- Deodorant
Mechanism of Action
- Antimicrobial and antiseptic activity through disruption of bacterial cell membranes
- Inhibition of bacterial enzyme activity
Contraindications
- Hypersensitivity to cetrimonium or other quaternary ammonium compounds
- Deep or puncture wounds
- Serious burns
Adverse Reactions
- Skin irritation
- Redness
- Itching
- Contact dermatitis
Drug Interactions
- Increased risk of skin irritation with concurrent use of soaps or other skin cleansers
- Incompatible with anionic surfactants
Curated Content: Needs Vetting Before Put to Clinical Use