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DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Quaternary ammonium compounds
dodeclonium bromide, combinations
D08AJ59
Forms & Strengths
- cream
- ointment
- solution
- 0.5-1% concentration
Adult Dosing
- apply 1-2 times daily
- amount dependent on affected area
Pediatric Dosing
- not established
- use with caution due to limited data
Indications
- skin disinfection
- preoperative skin preparation
- minor cuts and scrapes
Mechanism of Action
- bactericidal and bacteriostatic effects
- disrupts cell membrane integrity
- interferes with cellular metabolism
Contraindications
- known hypersensitivity to dodeclonium bromide
- deep or puncture wounds
- eye or ear canal use
Adverse Reactions
- skin irritation
- redness
- itching
- dryness
Drug Interactions
- incompatible with anionic formulations
- may reduce efficacy of some vaccines
- no significant interactions with systemic agents
Curated Content: Needs Vetting Before Put to Clinical Use