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DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Mercurial products
mercuric amidochloride
D08AK01
Adult Dosing
- Apply a thin layer to the affected skin area 1 to 2 times daily as directed by a healthcare professional.
Pediatric Dosing
- Safety and efficacy in pediatric patients have not been established; use is generally avoided due to systemic toxicity risks.
Indications
- Historical topical treatment for minor skin infections, psoriasis, and pediculosis.
Mechanism of Action
- Exerts antiseptic and parasiticidal effects through the precipitation of bacterial and fungal proteins by mercury ions.
Contraindications
- Hypersensitivity to mercury compounds
- Application to large, broken, or denuded areas of skin
- Prolonged or occlusive use
Adverse Reactions
- Local skin irritation and contact dermatitis
- Systemic mercury toxicity with prolonged application (neurological, renal, and gastrointestinal effects)
- Argyria-like discoloration with chronic absorption
Drug Interactions
- Concurrent use with other topical antiseptics or heavy metal-containing products may increase skin irritation and absorption risk
Curated Content: Needs Vetting Before Put to Clinical Use