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DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Mercurial products
mercuric iodide
D08AK30
Forms & Strengths
- Mercuric iodide is available as a topical powder
- Concentration is typically 1:1000 or 1:2000
- Also found in 2% and 5% ointment formulations
Adult Dosing
- Apply topically 1-3 times daily
- Specific dosing depends on the condition being treated
- Typically used for short durations, 7-14 days
Pediatric Dosing
- Use is generally not recommended in children due to toxicity concerns
- If used, apply topically 1-2 times daily under close medical supervision
- Dosing should be adjusted according to the child's age and weight
Indications
- Treatment of impetigo and other superficial skin infections
- Used for eczema, psoriasis, and seborrheic dermatitis
- May be applied to minor cuts and abrasions to prevent infection
Mechanism of Action
- Mercuric iodide has antibacterial properties
- It disrupts bacterial cell membranes, leading to cell death
- Also has antifungal properties, though less pronounced
Contraindications
- Hypersensitivity to mercury or iodine
- Pregnancy and lactation, due to mercury toxicity
- Kidney disease, as mercury can accumulate and worsen renal function
Adverse Reactions
- Local irritation, including redness and itching
- Allergic contact dermatitis
- Systemic mercury toxicity with prolonged or excessive use
Drug Interactions
- May interact with other heavy metals, increasing toxicity risk
- Concomitant use with nephrotoxic agents may increase kidney damage risk
- Avoid using with other topical agents that may enhance mercury absorption
Curated Content: Needs Vetting Before Put to Clinical Use