← Search & browse all drugs
DERMATOLOGICALS › ANTI-ACNE PREPARATIONS › ANTI-ACNE PREPARATIONS FOR TOPICAL USE › Preparations containing sulfur
bithionol
D10AB01
Forms & Strengths
- Tablet: 30mg, 50mg
- Powder for oral suspension
Adult Dosing
- 30-50mg/kg/day orally in 2 divided doses for 5 days for hookworm, roundworm, whipworm infections
- 100mg/day orally for 5 days for tapeworm infections
Pediatric Dosing
- 20-30mg/kg/day orally in 2 divided doses for 5 days for hookworm, roundworm, whipworm infections in children over 2 years
- 50mg/day orally for 5 days for tapeworm infections in children over 2 years
Indications
- Hookworm infections
- Roundworm infections
- Whipworm infections
- Tapeworm infections
Mechanism of Action
- Interferes with carbohydrate metabolism in worms
- Uncouples oxidative phosphorylation in parasites
Contraindications
- Hypersensitivity to bithionol
- Severe liver or kidney impairment
Adverse Reactions
- Gastrointestinal disturbance
- Abdominal pain
- Diarrhea
- Vomiting
- Allergic reactions
Drug Interactions
- May interact with other anthelminthic agents
- May increase risk of liver toxicity with concomitant use of hepatotoxic agents
Curated Content: Needs Vetting Before Put to Clinical Use