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sulfur

D10AB02

Forms & Strengths

Topical Ointment: 2%
5%
10%
Topical Lotion: 2%
5%
10%
Topical Bar Soap: 2%
5%
10%
Topical Shampoo: 2%
5%

Adult Dosing

Acne vulgaris: Apply thin layer to affected areas 1 to 3 times daily
Seborrheic dermatitis: Apply to affected scalp/skin areas, leave on for specified time then rinse, 1 to 2 times weekly
Scabies: Apply 5-10% sulfur ointment nightly for 3 consecutive nights
Rosacea: Apply thin layer to affected areas 1 to 2 times daily

Pediatric Dosing

Acne vulgaris (adolescents >12 years): Apply thin layer 1 to 3 times daily
Scabies (infants and children): Apply 2.5% to 10% precipitated sulfur in petrolatum nightly for 3 consecutive nights; safer alternative for neonates and infants

Indications

Acne vulgaris
Rosacea
Seborrheic dermatitis
Scabies
Dandruff

Mechanism of Action

Exerts mild keratolytic action, causing shedding of dead skin cells
Possesses antibacterial, antifungal, and antiparasitic (scabicidal) properties
Reacts with cysteine in skin proteins to form hydrogen sulfide and pentathionic acid, inhibiting growth of microorganisms

Contraindications

Hypersensitivity to elemental sulfur or any component of the formulation
Open wounds or severely broken skin (unless directed by physician)
Use in children under 2 years of age for indications other than scabies without medical supervision

Adverse Reactions

Skin irritation
Dryness
Erythema and scaling
Contact dermatitis
Stinging or burning sensation at application site
Unpleasant odor

Drug Interactions

Topical acne medications (e.g., benzoyl peroxide, tretinoin, salicylic acid): Increased risk of severe skin irritation and drying
Topical keratolytics: May cause cumulative irritant effects
Cosmetics or soaps containing alcohol or astringents: May increase skin drying and irritation

Curated Content: Needs Vetting Before Put to Clinical Use