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DERMATOLOGICALS › OTHER DERMATOLOGICAL PREPARATIONS › OTHER DERMATOLOGICAL PREPARATIONS › Medicated shampoos
cetrimide
D11AC01
Forms & Strengths
- Antiseptic cream 0.5%
- Antiseptic solution 0.1% to 1%
- Medicated shampoo 0.1%
Adult Dosing
- Minor cuts and wounds: Apply cream or solution to affected area 2-3 times daily as required.
- Scalp conditions (seborrhoeic dermatitis): Massage medicated shampoo into wet hair and scalp, leave for a few minutes, then rinse thoroughly.
Pediatric Dosing
- Minor cuts and wounds (Children > 2 years): Apply cream or solution to affected area 2-3 times daily.
- Infants and neonates: Avoid use due to risk of systemic absorption and severe skin irritation.
Indications
- Disinfection of minor cuts, abrasions, and minor burns
- Cleansing of skin and wounds
- Treatment of seborrhoeic dermatitis and dandruff of the scalp
Mechanism of Action
- Cationic quaternary ammonium surfactant.
- Disrupts cell membrane permeability, causing leakage of intracellular constituents and cell lysis.
- Exerts bacteriostatic or bactericidal activity primarily against gram-positive bacteria.
Contraindications
- Hypersensitivity to cetrimide or other quaternary ammonium compounds
- Application to the eyes or internal mucous membranes
- Use with occlusive dressings on broken skin due to risk of chemical burns
Adverse Reactions
- Skin irritation and contact dermatitis
- Erythema, burning, or stinging sensation at application site
- Chemical burns with prolonged contact or occlusion
Drug Interactions
- Incompatible with anionic surfactants (e.g., soap, sodium lauryl sulfate), which neutralize its antimicrobial activity.
- Incompatible with strong oxidizing agents and iodine preparations.
Curated Content: Needs Vetting Before Put to Clinical Use