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finasteride

D11AX10

Forms & Strengths

Oral tablet: 1 mg
Oral tablet: 5 mg

Adult Dosing

Benign Prostatic Hyperplasia (BPH): 5 mg orally once daily
Androgenetic Alopecia: 1 mg orally once daily

Pediatric Dosing

Not indicated for pediatric use

Indications

Treatment of symptomatic benign prostatic hyperplasia (BPH) to reduce risk of urinary retention and need for surgery
Treatment of male pattern hair loss (androgenetic alopecia) in men only

Mechanism of Action

Competitive inhibitor of type II 5-alpha-reductase, preventing the conversion of testosterone to dihydrotestosterone (DHT)

Contraindications

Hypersensitivity to finasteride or any component of the product
Pregnancy or women of childbearing potential due to risk of teratogenicity (abnormalities of external genitalia in male fetuses)
Pediatric patients

Adverse Reactions

Impotence
Decreased libido
Decreased ejaculate volume
Erectile dysfunction that may persist after discontinuation
Breast tenderness and enlargement (gynecomastia)
Hypersensitivity reactions including rash, pruritus, urticaria, and angioedema

Drug Interactions

No clinically significant drug interactions have been identified through pharmacokinetic interaction studies
CYP3A4 inhibitors (e.g., ketoconazole) may theoretically increase plasma concentrations, though rarely clinically significant

Curated Content: Needs Vetting Before Put to Clinical Use