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GENITO URINARY SYSTEM AND SEX HORMONES › GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS › ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS › Other antiinfectives and antiseptics
clodantoin
G01AX01
Adult Dosing
- 1 applicatorful (approx. 5g) intravaginally once or twice daily for 14 to 21 days
Pediatric Dosing
- Safety and efficacy not established in pediatric patients
Indications
- Treatment of vulvovaginal candidiasis
Mechanism of Action
- Fungicidal/fungistatic antifungal agent that alters fungal cell membrane permeability, leading to leakage of intracellular constituents
Contraindications
- Hypersensitivity to clodantoin or any components of the formulation
Adverse Reactions
- Local vaginal irritation
- Burning
- Itching
- Erythema
Drug Interactions
- No significant systemic drug-interactions expected due to minimal systemic absorption from vaginal application
- May weaken latex condoms and diaphragms
Curated Content: Needs Vetting Before Put to Clinical Use