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GENITO URINARY SYSTEM AND SEX HORMONES › GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS › ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS › Other antiinfectives and antiseptics
copper usnate
G01AX15
Forms & Strengths
- Vaginal suppository: 250mg
- Vaginal tablet: 200-250mg
Adult Dosing
- 1 suppository or tablet intravaginally once daily for 7-14 days
- Use as directed by healthcare provider
Pediatric Dosing
- Safety and efficacy not established for pediatric patients
- Use is not recommended for pediatric patients
Indications
- Treatment of trichomoniasis
- Treatment of bacterial vaginosis
- Relief of symptoms associated with vaginal infections
Mechanism of Action
- Copper ions have antimicrobial properties
- Copper ions disrupt microbial cell membranes and DNA
- USNATE (undecylenic acid salt) enhances copper ion release
Contraindications
- Hypersensitivity to copper or undecylenic acid
- Pregnancy (category C)
- Breastfeeding
Adverse Reactions
- Vaginal irritation
- Burning sensation
- Itching
- Abdominal pain
- Allergic reactions (rare)
Drug Interactions
- Concurrent use with other vaginal products may reduce efficacy
- Copper ions may interact with certain metals (e.g., zinc)
- Potential interaction with warfarin (increased INR risk)
Curated Content: Needs Vetting Before Put to Clinical Use