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GENITO URINARY SYSTEM AND SEX HORMONES › OTHER GYNECOLOGICALS › CONTRACEPTIVES FOR TOPICAL USE › Intrauterine contraceptives
plastic IUD with copper
G02BA02
Forms & Strengths
- Intrauterine device (IUD) containing copper T380A
- Surface area of copper: 380 mm²
Adult Dosing
- Insert into uterine cavity as a single intrauterine contraceptive
- Effective for up to 10 years
- Emergency contraception: insert within 5 days of unprotected intercourse
Pediatric Dosing
- Indicated for adolescents of reproductive age (menarchal females)
- Dosing identical to adult dosage
Indications
- Intrauterine contraception
- Emergency contraception
Mechanism of Action
- Releases copper ions into the uterine cavity
- Induces a local sterile inflammatory foreign body reaction
- Alters cervical mucus, inhibits sperm motility and viability, and prevents fertilization
Contraindications
- Pregnancy or suspected pregnancy
- Anatomical distortion of the uterine cavity
- Acute pelvic inflammatory disease or active infections
- Postpartum endometritis or infected abortion in past 3 months
- Known or suspected uterine or cervical malignancy
- Undiagnosed abnormal uterine bleeding
- Wilson's disease or known hypersensitivity to copper
Adverse Reactions
- Increased menstrual bleeding and dysmenorrhea
- Abdominal/pelvic pain
- Expulsion of the device
- Uterine perforation
- Pelvic inflammatory disease (PID) shortly after insertion
Drug Interactions
- No significant systemic pharmacokinetic drug interactions known
- Efficacy may theoretically be affected by drugs altering the inflammatory response, though clinically insignificant
Curated Content: Needs Vetting Before Put to Clinical Use