← Search & browse all drugs
GENITO URINARY SYSTEM AND SEX HORMONES › OTHER GYNECOLOGICALS › CONTRACEPTIVES FOR TOPICAL USE › Intrauterine contraceptives
plastic IUD with progestogen
G02BA03
Forms & Strengths
- T-shaped plastic IUD with 52mg levonorgestrel
- Hormone-releasing IUD with 19.5mg levonorgestrel
- Cylindrical-shaped IUD with 36mg levonorgestrel
Adult Dosing
- Insertion within 7 days of menstruation or after 6 weeks postpartum
- Replacement every 3-5 years depending on IUD type and product
- Insertion during breastfeeding after 4 weeks postpartum
Pediatric Dosing
- Not recommended for use before menarche
- Use with caution in adolescents with primary amenorrhea or hypothalamic amenorrhea
- Insertion in adolescents only if benefits outweigh risks
Indications
- Contraception for up to 3-5 years
- Treatment of heavy menstrual bleeding
- Management of dysmenorrhea
- Endometrial protection during estrogen replacement therapy
Mechanism of Action
- Local progestogenic effects on the endometrium
- Thickening of cervical mucus to prevent sperm penetration
- Inhibition of ovulation in some cases
- Thin, atrophic endometrium to prevent implantation
Contraindications
- Known or suspected pregnancy
- Undiagnosed abnormal vaginal bleeding
- Current or past pelvic inflammatory disease
- Known or suspected malignancy of breast or reproductive organs
Adverse Reactions
- Spotting or irregular bleeding
- Perforation of uterus
- Expulsion of IUD
- Breast tenderness
- Mood changes
- Headache
Drug Interactions
- No known significant interactions with other medications
- Concomitant use with anticoagulants may increase bleeding risk
- Potential decreased efficacy of IUD with concomitant use of certain antibiotics
Curated Content: Needs Vetting Before Put to Clinical Use