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GENITO URINARY SYSTEM AND SEX HORMONES › SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM › HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE › Progestogens and estrogens, fixed combinations
quingestanol and ethinylestradiol
G03AA02
Forms & Strengths
- quingestanol 0.05mg and ethinylestradiol 0.03mg tablets
Adult Dosing
- 1 tablet orally once daily for 21 days, followed by 7 days of no tablets
Pediatric Dosing
- not recommended for use in children prior to menarche
Indications
- contraception
- regulation of menstrual cycle
- treatment of dysmenorrhea
- treatment of acne
Mechanism of Action
- inhibits ovulation by suppressing luteinizing hormone release
- increases viscosity of cervical mucus to prevent sperm penetration
Contraindications
- pregnancy
- breast cancer
- liver disease
- thromboembolic disorders
Adverse Reactions
- nausea
- vomiting
- headache
- breast tenderness
- weight gain
Drug Interactions
- rifampin decreases contraceptive efficacy
- anticonvulsants decrease contraceptive efficacy
- troleandomycin increases risk of adverse effects
Curated Content: Needs Vetting Before Put to Clinical Use