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GENITO URINARY SYSTEM AND SEX HORMONES › SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM › PROGESTOGENS › Pregnadien derivatives
chlormadinone
G03DB06
Forms & Strengths
- Tablets: 2mg, 5mg
- Oral dosage forms
Adult Dosing
- 2mg to 5mg daily for contraception
- Dosage varies depending on specific condition being treated
Pediatric Dosing
- Not recommended in children prior to menarche
- Dosage for pediatric patients should be determined by a healthcare provider
Indications
- Oral contraception
- Treatment of menstrual disorders
- Dysmenorrhea
- Endometriosis
Mechanism of Action
- Progestin-only action
- Inhibits ovulation
- Thickens cervical mucus
- Alters the endometrium
Contraindications
- Pregnancy
- Undiagnosed vaginal bleeding
- Active thrombophlebitis or thromboembolic disorders
- Liver dysfunction
Adverse Reactions
- Breast tenderness
- Nausea
- Headache
- Dizziness
- Weight gain
Drug Interactions
- May interact with CYP3A4 inhibitors or inducers
- Concomitant use with aminoglutethimide may decrease efficacy
- May interact with anticonvulsants
Curated Content: Needs Vetting Before Put to Clinical Use