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GENITO URINARY SYSTEM AND SEX HORMONES › UROLOGICALS › UROLOGICALS › Other urologicals
phenazopyridine
G04BX06
Forms & Strengths
- Tablets: 95 mg, 100 mg, 200 mg
- Oral solution: 100 mg/5 mL, 200 mg/5 mL
Adult Dosing
- 200 mg tid after meals
- Typical duration: 2 days
Pediatric Dosing
- 4-8 mg/kg daily, divided into 3 equal doses
- Maximum daily dose: 200-400 mg
Indications
- Symptomatic relief of dysuria, urgency, and frequency
- Interstitial cystitis
- Urethral syndrome
- Prostatitis
- Urinary tract infection
Mechanism of Action
- Local anesthetic effect on urinary tract mucosa
- Azobenzene structure, metabolized to a local analgesic
Contraindications
- Renal insufficiency or renal failure
- Hepatic insufficiency or liver failure
Adverse Reactions
- Headache
- Nausea
- Dizziness
- GI upset
- Methemoglobinemia (rare, but potentially severe)
Drug Interactions
- Potential interactions with anticoagulants
- Possible increased phenytoin levels
- Interaction with MAOIs, avoid co-administration
Curated Content: Needs Vetting Before Put to Clinical Use