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GENITO URINARY SYSTEM AND SEX HORMONES › UROLOGICALS › UROLOGICALS › Other urologicals
sodium salicylate and methenamine
G04BX17
Forms & Strengths
- Tablets: 325mg sodium salicylate, 162mg methenamine
- Capsules: 500mg sodium salicylate, 250mg methenamine
Adult Dosing
- 1-2 tablets/capsules every 12 hours
- Max: 4 tablets/capsules in 24 hours
Pediatric Dosing
- Not recommended for children under 12 years
- 12-18 years: same as adult dose
Indications
- Urinary tract infections
- Irritative symptoms of lower urinary tract
- Chronic urethritis
Mechanism of Action
- Sodium salicylate: analgesic, anti-inflammatory
- Methenamine: urinary antibacterial, acidifying agent
Contraindications
- Allergy to salicylates or methenamine
- Gastrointestinal ulcers
- Bleeding disorders
Adverse Reactions
- Gastrointestinal upset
- Nausea
- Vomiting
- Allergic reactions
Drug Interactions
- Warfarin: increased anticoagulant effect
- Diuretics: reduced efficacy
- NSAIDs: increased risk of GI bleeding
Curated Content: Needs Vetting Before Put to Clinical Use