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ANTIINFECTIVES FOR SYSTEMIC USE › IMMUNE SERA AND IMMUNOGLOBULINS › IMMUNOGLOBULINS › Specific immunoglobulins
staphylococcus immunoglobulin
J06BB08
Forms & Strengths
- Injection solution: 100-200 mg/mL
- Lyophilized powder for injection: 100-200 mg/vial
Adult Dosing
- Varies depending on indication and product, typically 100-400 mg/kg
- Dose may be repeated at intervals of 3-4 weeks
Pediatric Dosing
- Safety and efficacy not established in children under 2 years
- For children 2-12 years: dose as for adults, adjusted for body weight
Indications
- Prevention of staphylococcal infections in high-risk patients
- Treatment of severe or complicated staphylococcal infections
Mechanism of Action
- Passive immunization with antibodies against staphylococcal antigens
- Neutralizes staphylococcal toxins and enhances opsonization
Contraindications
- Hypersensitivity to immunoglobulins or components
- IgA deficiency with antibodies against IgA
Adverse Reactions
- Hypersensitivity reactions, anaphylaxis, or serum sickness
- Headache, fatigue, chills, fever, or injection-site reactions
Drug Interactions
- Concomitant use with live vaccines: possible reduced immunological response
- Interference with immune response to killed-virus vaccines
Curated Content: Needs Vetting Before Put to Clinical Use