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ANTIINFECTIVES FOR SYSTEMIC USE › IMMUNE SERA AND IMMUNOGLOBULINS › IMMUNOGLOBULINS › Specific immunoglobulins
encephalitis, tick borne immunoglobulin
J06BB12
Forms & Strengths
- 200 mg/mL solution for injection
Adult Dosing
- 1.6 to 2.4 mL/kg body weight as a single dose
- Administered intravenously or intramuscularly
Pediatric Dosing
- 20 mg/kg body weight as a single dose
- Administered intravenously or intramuscularly
- For children under 1 year: 30 mg/kg
- For children between 1-6 years: 20-30 mg/kg
Indications
- Post-exposure prophylaxis against tick-borne encephalitis
- Treatment of tick-borne encephalitis
- Immunoprophylaxis in high-risk groups
Mechanism of Action
- Passive immunization with specific antibodies against tick-borne encephalitis virus
- Neutralizing antibodies bind to the virus, preventing infection
Contraindications
- Hypersensitivity to immunoglobulins
- IgA deficiency with anti-IgA antibodies
- Severe reactions to previous immunoglobulin administration
Adverse Reactions
- Chills
- Fatigue
- Headache
- Fever
- Nausea
- Dizziness
- Local reactions at injection site
Drug Interactions
- Live vaccines: may interfere with immune response
- Immunosuppressants: may reduce efficacy of immunoglobulin
Curated Content: Needs Vetting Before Put to Clinical Use