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ANTIINFECTIVES FOR SYSTEMIC USE › VACCINES › BACTERIAL VACCINES › Haemophilus influenzae B vaccines
haemophilus influenzae B, combinations with toxoids
J07AG51
Forms & Strengths
- Injection suspension: 0.5ml single dose vial
- Conjugate 10mcg, 25mcg per 0.5ml dose
Adult Dosing
- Administer one 0.5ml dose IM to individuals older than 5 years
- Typically do not administer boosters after age 5
Pediatric Dosing
- 2, 4, 6, and 12-15 months: administer 0.5ml IM
- May administer 0.5ml IM dose to children older than 12 months if primary series missed
Indications
- Prevention of invasive infections caused by Haemophilus influenzae type b
- Prevention of diseases such as epiglottitis, meningitis, and pneumonia
Mechanism of Action
- Induces active immunity against Haemophilus influenzae type b
- Conjugation with toxoids enhances immunogenicity in infants
Contraindications
- Severe allergic reaction to a previous dose
- Hypersensitivity to any vaccine component
Adverse Reactions
- Redness, swelling, and pain at the injection site
- Fever, fussiness, and loss of appetite
Drug Interactions
- May interfere with immune response to other vaccines given simultaneously
- Administer with caution to patients receiving immunosuppressive therapy
Curated Content: Needs Vetting Before Put to Clinical Use