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ANTIINFECTIVES FOR SYSTEMIC USE › VACCINES › BACTERIAL VACCINES › Pneumococcal vaccines
pneumococcus, purified polysaccharides antigen
J07AL01
Forms & Strengths
- injection, 25 mcg of pneumococcal polysaccharide
- 0.5 mL single-dose vials
Adult Dosing
- 0.5 mL IM injection
- single dose for adults 65 years and older
- single dose for adults 19-64 years with certain medical conditions
Pediatric Dosing
- not recommended for children under 2 years
- 0.5 mL IM injection for children 2 years and older with certain medical conditions
- dosing based on child's age and medical condition
Indications
- active immunization against pneumococcal disease
- prevention of invasive disease caused by Streptococcus pneumoniae
- prevention of pneumococcal pneumonia
Mechanism of Action
- stimulates immune system to produce antibodies
- induces immunity to pneumococcal capsular polysaccharides
- prevents invasive pneumococcal disease by promoting opsonization and phagocytosis
Contraindications
- severe allergic reaction to pneumococcal polysaccharide vaccine
- allergy to any component of the vaccine
Adverse Reactions
- injection site pain, redness, and swelling
- fatigue, headache, and muscle pain
- fever, chills, and nausea
Drug Interactions
- may interfere with immune response to other vaccines
- caution with immunosuppressants and immunomodulators
- avoid concurrent administration with other vaccines
Curated Content: Needs Vetting Before Put to Clinical Use