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ANTIINFECTIVES FOR SYSTEMIC USE › VACCINES › VIRAL VACCINES › Influenza vaccines
influenza, virus like particles
J07BB04
Forms & Strengths
- Intramuscular suspension: 45 mcg hemagglutinin (HA) per strain per 0.5 mL pre-filled syringe (Quadrivalent)
Adult Dosing
- 0.5 mL intramuscularly once annually before the influenza season
Pediatric Dosing
- Ages 18 years and older: 0.5 mL intramuscularly once annually (Note: Recombinant/VLP influenza vaccines are typically indicated for adults 18 years and older; refer to specific product labeling for pediatric indications if applicable)
Indications
- Active immunization for the prevention of disease caused by influenza A and B subtypes contained in the vaccine in adults
Mechanism of Action
- Induces humoral immune response against hemagglutinin surface glycoproteins of influenza virus strains, neutralizing viral infectivity and preventing attachment to host cell receptors
Contraindications
- History of severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or previous influenza vaccination
Adverse Reactions
- Pain, tenderness, erythema, and swelling at the injection site
- Headache
- Fatigue
- Myalgia
- Malaise
Drug Interactions
- Immunosuppressive therapies may diminish the immune response to the vaccine
- Concomitant administration with other vaccines should be given at separate injection sites
Curated Content: Needs Vetting Before Put to Clinical Use