← Search & browse all drugs
ANTIINFECTIVES FOR SYSTEMIC USE › VACCINES › VIRAL VACCINES › Varicella zoster vaccines
zoster, purified antigen
J07BK03
Forms & Strengths
- 0.65mL suspension for injection
- contains 19,400 to 47,400 PFU/mL
- single-dose vials
Adult Dosing
- 0.65mL suspension as a single dose
- administered intramuscularly
- recommended for individuals 50 years and older
Pediatric Dosing
- not approved for individuals under 18 years
- safety and efficacy not established
Indications
- prevention of herpes zoster (shingles)
- reduction of postherpetic neuralgia
Mechanism of Action
- stimulates immune system to produce antibodies
- cell-mediated immune response against varicella-zoster virus
Contraindications
- severe allergic reactions to vaccine components
- fever over 38.3°C
- active untreated tuberculosis
Adverse Reactions
- injection site reactions
- myalgia
- fatigue
- headache
- shivering
Drug Interactions
- immunosuppressive therapies
- tuberculin skin tests
- other vaccines
Curated Content: Needs Vetting Before Put to Clinical Use