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ANTIINFECTIVES FOR SYSTEMIC USE › VACCINES › VIRAL VACCINES › Covid-19 vaccines
covid-19, protein subunit
J07BN04
Forms & Strengths
- 0.5ml solution for injection, containing 5mcg antigen
- single-dose prefilled syringe
- single-dose vial
Adult Dosing
- primary series: 2 doses, 21 days apart
- booster dose: 1 dose, at least 6 months after primary series
Pediatric Dosing
- children 5-11 years: primary series, 2 doses, 21 days apart, 5mcg
- adolescents 12 years and older: same dosage as adults
Indications
- prevention of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2
- active immunization to prevent COVID-19 in individuals 5 years of age and older
Mechanism of Action
- stimulates immune response to SARS-CoV-2 spike protein
- induces neutralizing antibodies to prevent infection and disease
Contraindications
- severe allergic reaction to any component of the vaccine
- anaphylaxis after previous dose of COVID-19 vaccine
Adverse Reactions
- injection site pain, redness, and swelling
- fatigue, headache, and muscle pain
- lymphadenopathy, fever, chills, and joint pain
Drug Interactions
- immunocompromised patients may have reduced response to vaccine
- antipyretics and analgesics may be used to manage post-vaccination symptoms
Curated Content: Needs Vetting Before Put to Clinical Use